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About Pernex® Gel

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Pernex® Gel is manufactured by Oaknet Healthcare. This is a topical treatment for mild to moderate acne. Pernex® Gel has strong antibacterial and exfoliating properties, it peels off the dead cells from the skin surface and fights the acne-causing bacteria.

Pernex® Gel contains Benzoyl Peroxide (BPO) as an active ingredient. It is an organic chemical compound of peroxides class with potent bactericidal, sebostatic, comedolytic, and anti-inflammatory activities.

Acne is an inflammatory skin disorder that appears due to the overabundance of P. acnes (Propionibacterium acnes) bacteria in the skin. These germs start proliferating within the clogged pores, and soon our immune system responds to this growth with inflammation. Rapid reproduction of P. acnes is associated with genetic predisposition or increase in androgenic hormones. The symptoms of acne include non-inflamed comedones, whiteheads, pimples, cysts, and constantly clogged pores.

MOA (mechanism of action):

Benzoyl Peroxide is lipophilic (dissolving in fats and oils) drug, that easily penetrates the stratum corneum (outermost layer of the skin). Entering the pilosebaceous follicle, BPO metabolizes to benzoic acid and hydrogen peroxide and releases free radical oxygen that acts as a bactericidal towards P. acnes. As an exfoliant, Benzoyl Peroxide increases the turnover rate of epithelial cells and peels off the dead cells residue from the skin, thereby unclogging the pores.


Pernex® Gel is for external use only. Do not apply to your eyes or eyelids, lips, mouth, inside of the nose, private parts, and any other mucosal surface.

Apply Pernex® Gel 1-2 times daily. This gel should be applied for 6-8 weeks at least. Consult your doctor regarding the further use of Pernex® Gel.

In case your acne has not improved after 6-8 weeks of treatment, discontinue the Pernex® Gel use and seek medical advice.

How to use Pernex® Gel:

1. Wash your hands and the affected areas with mild soap or cleanser, pat dry.

2. Apply a thin layer of Pernex® Gel to the areas where you tend to get breakouts, not just to each spot.

3. Rub gently until absorbed.

4. Wash your hands after the gel application.

5. Wait for about 15 minutes and apply a moisturizer or emollient.


If dryness and severe peeling of the skin appear at the start of the Pernex® Gel treatment course, alter the number of daily applications or apply the gel every other day. When the tolerance to the gel is developed, continue your regular application schedule.

During the first week or two of the Pernex® Gel treatment course you may notice a mild burning sensation after the application.

Use sunscreen during the Pernex® Gel treatment course.

As Pernex® Gel makes the skin drier than usual, you should use skin moisturizers during the treatment course.

Do not apply Pernex® Gel to the broken skin, open wounds, cuts or burns (sunburns and included).

Be careful while applying Pernex® Gel to sensitive areas like neck.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not apply a double dose.


Do not exceed the doctor's recommended dose. If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at a room temperature from 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away the tube after the expiration date. Keep away from children.

Side effects

The most common side effects associated with the use of Pernex® Gel are:

  • dry skin
  • peeling of the skin
  • redness
  • burning sensation
  • itching
  • stinging
  • irritation (irritant contact dermatitis)

Side effects occurrence does not only depend on the medication you are using, but also on your overall health and other factors.


Do not apply Pernex® Gel if you are allergic to Benzoyl Peroxide.

Do not apply Pernex® Gel if you are allergic to any of the other ingredients comprised in Pernex® Gel.

Do not use Pernex® Gel if you are applying any acne treatment containing salicylic acid, retinoids (tretinoin, adapelene, tazarotene, isotretinoin), azelaic acid or sulfone products (dapsone, promin).

Do not use Pernex® Gel if you are taking any medication containing corticosteroids (fluocinolone), benzene derivatives (hydroquinone), phenols (mequinol) or sodium thiosulfate.

Do not use Pernex® Gel if you have asthma or hypersensitivity to benzoic acid or its derivatives (cinnamon, certain topical anesthetics, etc.).

Do not use Pernex® Gel if you have dermatitis, seborrhea, eczema, skin inflammation or damage including sunburn or windburn.

Do not use Pernex® Gel if you are pregnant or breastfeeding without your doctor’s approval.

Do not use Pernex® Gel in patients under the age of 12.

Do not take by mouth. Pernex® Gel is for use only on the skin.

Avoid getting Pernex® Gel on your hair or any colored fabric, as the gel can bleach them.

Do not use Pernex® Gel more than 2 times a day.

Q: Can I treat rosacea with Pernex® Gel?

A: No. Pernex® Gel should be used only as an acne treatment.

Q: Is Pernex® Gel safe for my child?

A: Pernex® Gel is completely safe for patients over 12 years old.

Q: Can I use Pernex® Gel during pregnancy?

A: Although Pernex® Gel is considered as mostly safe for the use in pregnant women, you should not start the treatment course without your doctor’s approval.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 15.00 per order
EMS  Trackable, where available 5-9 business days USD 25.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 15.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 25.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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