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About Fildena® XXX

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Description

Fildena® XXX is used to treat men with erectile dysfunction, also known as impotence, which is an inability to sustain a satisfactory erection to complete intercourse. The drug is utilized in the treatment of pulmonary arterial hypertension as well. It reduces symptoms associated with the condition, including shortness of breath, fatigue, chest pain, etc., and enhances exercise capacity. The active substance present in the formulation is Sildenafil, an inhibitor of cGMP specific phosphodiesterase type 5 (PDE5), which enhances erectile function by relaxing the smooth muscle and increasing penile blood flow. Due to the medicine’s vasodilatory effect, it also helps reduce symptoms in patients suffering from pulmonary arterial hypertension. Fildena® XXX comes in banana, orange, strawberry, and pineapple flavors.

Indications

Treatment of impotence in adult males.

Treatment of pulmonary arterial hypertension.

MOA (mechanism of action)

The physiologic mechanism of erection of the penis involves the release of nitric oxide (NO) which activates the enzyme guanylate cyclase, resulting in increased levels of cyclic guanosine monophosphate (cGMP). This enhances the smooth muscle relaxation in the corpus cavernosum and allows inflow of blood. Sildenafil improves the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5) which is responsible for the degradation of cGMP in the corpus cavernosum. When sexual stimulation causes a local release of NO, inhibition of PDE5 by Sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.

Sildenafil is an inhibitor of cGMP specific phosphodiesterase type5 (PDE5) in the smooth muscle of the pulmonary vasculature, where PDE5 is responsible for the degradation of cGMP. Sildenafil, therefore, increases cGMP within pulmonary vascular smooth muscle cells resulting in relaxation. In patients with pulmonary hypertension, this can lead to vasodilation of the pulmonary vascular bed and, to a lesser degree, vasodilatation in the systemic circulation.

Dosage and administration

Fildena® XXX comes in the form of a chewable tablet with 4 different flavors: banana, orange, strawberry, pineapple. It should be chewed, not swallowed. For the treatment of impotence, the medicine is used once a day, 30 to 60 minutes before sexual activity. Its effect can last up to 4 hours. For patients with pulmonary arterial hypertension, the dosing regimen of Fildena® XXX should be prescribed by a doctor and taken about 4-6 hours apart. Avoid consuming alcohol, grapefruit juice or fatty food while taking this medicine because it may alter the way it works.

Missed dose

If you miss a dose of Fildena® XXX you should take it as soon as you remember. If it is the time for the next dose, go on with regular dosing schedule. Do not take more than one dose of this medicine when using it for the treatment of erectile dysfunction.

Overdose

In cases of overdose, seek emergency medical attention or contact your doctor immediately.

Manufacturer

Fortune Health Care

Side effects

The most common side effects associated with Fildena® XXX are:

  • headache
  • dizziness
  • sleeplessness
  • skin rash
  • flushing
  • abnormally low blood pressure
  • abnormal vision
  • temporary vision loss
  • hearing loss
  • persistent and painful erection of the penis
  • prolonged erection (lasting for more than 4 hours)
  • stuffy nose
  • urinary tract infection
  • indigestion
  • diarrhea

Side effect occurrence does not only depend on the medication you are taking but also on your overall health and other factors.

Contraindications

Fildena® XXX must not be used in the following cases:

  • known hypersensitivity to Sildenafil or any of the drug’s excipients.
  • co-administration with organic nitrates in any form as Sildenafil can potentiate the hypotensive effects of nitrates.
Warnings and precautions

Exercise caution with Fildena® XXX if you have any of the following health conditions:

  • left ventricular outflow obstruction (e.g., aortic stenosis, idiopathic hypertrophic subaortic stenosis);
  • severely impaired autonomic control of blood pressure;
  • myocardial infarction, stroke, or life-threatening arrhythmia within the last 6 months;
  • resting hypotension (BP <90/50) or hypertension (BP >170/110);
  • cardiac failure or coronary artery disease causing unstable angina;
  • retinitis pigmentosa (a minority of these patients have genetic disorders of retinal phosphodiesterases);
  • prolonged erection greater than 4 hours and priapism (painful erections greater than 6 hours in duration). If such occurs, the patient should seek immediate medical assistance. If priapism is not treated immediately, penile tissue damage and permanent loss of potency could result.
  • bleeding disorders and/ or active peptic ulcers;
  • deformation of the penis (such as angulation, cavernosal fibrosis or Peyronie’s disease);
  • sickle cell anemia, multiple myeloma, or leukemia.

Drug interactions

  • riociguat
  • ritonavir
  • alpha-blockers
  • bosentan
  • cimetidine
  • erythromycin
  • nitrates
  • saquinavir
  • ketoconazole or itraconazole
  • magnesium hydroxide/aluminum hydroxide antacids

Q: What is Fildena® XXX?

A: Ths is a drug indicated for the treatment of male impotence, sexual dysfunction which affects the ability to develop or maintain an erection. The medicine is also beneficial in treating pulmonary arterial hypertension

Q: How to take these tablets?

A: This medication should be administered orally. The chewable tablets should not be swallowed whole. Do not take more of for a longer period of time than recommended by your doctor.

Q: Can I take Fildena® XXX during pregnancy or if I’m a nursing mother?

A: It is not advisable to use this medication during pregnancy or when breastfeeding. Please consult your doctor about all the benefits and the possible risks before taking this medicine.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 15.00 per order
EMS  Trackable, where available 5-9 business days USD 25.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 15.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 25.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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This is exactly how your parcel will look like (pictures of a real shipping item). It has a look of a regular private letter and does not disclose its contents. Size - 9.4x4.3x0.3 inches (24x11x0.7cm).

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