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About Mildronate®

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Description

Mildronate® is a clinically used cardioprotective drug with Meldonium as an active ingredient, which mechanism of action is based on the regulation of energy metabolism pathways through L-carnitine lowering effect.

Meldonium is a structural analog of a precursor of carnitine - gamma-butyrobetaine (GBB), a substance that is found in every cell of the human body. Meldonium prevents the accumulation of cytotoxic intermediate products of fatty acid beta-oxidation in ischemic tissues and blocks this highly oxygen-consuming process.

Mildronate® is indicated for use in the following cases:

  • cardiovascular diseases: stable angina pectoris, chronic heart failure (NYHA functional class I-III), cardiomyopathy, functional cardiovascular disorders;
  • acute and chronic ischaemic cerebrovascular disorders;
  • decreased work performance, physical and psychoemotional overload;
  • during a recovery period after cerebrovascular disorders, head trauma and encephalitis.
Method of administration

The dosage of this medication depends on the patient's medical condition and should be recommended by a healthcare professional.

Mildronate® is for oral administration. The capsules should be swallowed with water. The medicine can be used before or after the meal.

It is advised to take Mildronate® in the first half of the day because of a possible stimulating effect.

Missed dose

Do not take a double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule

Overdose

Mildronate® is low-toxic and does not cause any side effects which may threaten the life of patients. If an overdose occurs and you don't feel good you should visit your doctor or health care provider immediately. In case of severe overdosage, it is necessary to control liver and kidneys function.

Storage

Store at room temperature between 15°C and 30°C (59°F and 86°F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Manufacturer

Grindex

Side effects

Mildronate® is usually well-tolerated. In rare cases, you may experience:

  • headache
  • itching
  • tachycardia
  • hypotension
  • dyspepsia
  • agitation
  • excitement
Contraindications

Hypersensitivity to the active substance Meldonium or any of the medicine’s components.

Severe hepatic and/or renal insufficiency.

Pregnancy and breastfeeding.

In children and adolescents under 18 years of age.

Warnings and precautions

In patients with a history of hepatic and/or renal disorders, using this medicine caution should be exercised (monitoring of liver and/or kidney functions should be performed).

Avoid Mildronate®’s co-administration with such cardiovascular agents as nitroglycerine, nifedipine, beta-adrenoblockers, hypotensive agents or peripheral vasodilators as this medication may intensify their actions.

Q: What is Mildronate®?

A: Mildronate® is a nootropic, vasodilator and CNS stimulant developed for the treatment of heart ischemia and its consequences, brain circulation disorders and for improving physical capacity and mental function in healthy people.

Q: How does this medicine work?

A: Meldonium is a structural analog of a precursor of carnitine - gamma-butyrobetaine (GBB), a substance that is found in every cell of the human body, which prevents the accumulation of cytotoxic intermediate products of fatty acid beta-oxidation in ischemic tissues and blocks this highly oxygen-consuming process.

Q: How should I use this medication?

A: Mildronate® is for oral administration. The capsules should be swallowed with water. The medicine can be used before or after the meal. It is advised to take Mildronate® in the first half of the day because of a possible stimulating effect.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 15.00 per order
EMS  Trackable, where available 5-9 business days USD 25.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 15.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 25.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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